Product: (Z)-Mutagenic Impurity of Tenofovir Disoproxil
Mannose Phosphate Isomerase Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human MPI. The exact sequence is proprietary.
|
| Localization |
Cytoplasm
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MPI
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Mouse (84%), Chimpanzee (99%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Mannose Phosphate Isomerase Antibody
- CDG1B
- EC 5.3.1
- EC 5.3.1.8
- FLJ39201
- mannose phosphate isomerase
- mannose-6- phosphate isomerase
- mannose-6-phosphate isomerase
- Phosphohexomutase
- phosphomannose isomerase 1
- Phosphomannose isomerase
- PMI
- PMI1phosphohexomutase
Background
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.