Product: Integrin Antagonist 1 (hydrochloride)
MEK5 Antibody Summary
| Immunogen |
Synthetic peptide corresponding to a portion of human MEK5.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MAP2K5
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is useful in Immunohistochemistry and Western blot (Detects a band of ~42kDa).
|
Reactivity Notes
Recognizes Human, Mouse, Rat, Canine, Primate, Rabbit, Sheep and Xenopus MEK5.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2)
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MEK5 Antibody
- HsT17454
- MAP kinase kinase 5
- MAP kinase kinase MEK5b
- MAP2K5
- MAPK/ERK kinase 5
- MAPKK 5
- MAPKK5
- MAPKK5EC 2.7.12.2
- MEK5
- MEK5MEK 5
- mitogen-activated protein kinase kinase 5
- MKK5
- PRKMK5
- PRKMK5dual specificity mitogen-activated protein kinase kinase 5
Background
MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.