MED7 Antibody (2D7) Summary
| Immunogen |
CRSP9 (AAH05250, 1 a.a. ~ 234 a.a) full length recombinant protein with GST tag.MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP
|
| Specificity |
CRSP9 (2D7)
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MED7
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
|
Reactivity Notes
Human, Mouse, Rat.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for MED7 Antibody (2D7)
- Activator-recruited cofactor 34 kDa component
- Cofactor required for Sp1 transcriptional activation subunit 9
- cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)
- cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa
- CRSP33CRSP complex subunit 9
- CRSP9hMED7
- mediator complex subunit 7ARC34
- mediator of RNA polymerase II transcription subunit 7
- MGC12284
- RNA polymerase transcriptional regulation mediator subunit 7 homolog
- Transcriptional coactivator CRSP33
Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.