MED13 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 750 and 800 of human thyroid hormone receptor associated protein 1 (thyroid hormone receptor-associated protein, 240 kDa) using the numbering given in entry NP_005112.2 (GeneID 996
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| Predicted Species |
Primate (100%), Ferret (100%), Canine (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MED13
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Publications |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Chimpanzee, White-tufted-ear marmoset, European domestic ferret and African elephant.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for MED13 Antibody
- Activator-recruited cofactor 250 kDa component
- KIAA0593HSPC221
- mediator complex subunit 13ARC250
- mediator of RNA polymerase II transcription, subunit 13 homolog
- THRAP1mediator of RNA polymerase II transcription subunit 13
- thyroid hormone receptor associated protein 1
- Thyroid hormone receptor-associated protein 1
- Thyroid hormone receptor-associated protein complex 240 kDa component
- thyroid hormone receptor-associated protein complex component TRAP240
- thyroid hormone receptor-associated protein, 240 kDa subunit
- Trap240
- TRAP240DRIP250
- Vitamin D3 receptor-interacting protein complex component DRIP250
Background
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.