Lewis A Blood Group Antigen Antibody (7LE) Summary
| Immunogen |
Mucin isolated by size-exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglios classification).
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| Specificity |
The antibody 7LE recognizes Lewisa blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed in colonic epithelial cells. Lewisa may be useful for detection of gastrointestinal, pancreatic and colorectal tumors.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
ABO
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Purity is > 95% (by SDS-PAGE). For Immunohistochemistry-Paraffin use heat mediated antigen retrieval (sodium citrate).
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
15mM Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Protein A purified
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Background
This antibody recognizes FUT3/Blood Group Lewis A, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed in colonic epithelial cells. FUT3/Blood Group Lewis A may be useful for detection of gastrointestinal, pancreatic and colorectal tumors.