Product: AZD9058 (hydrochloride)
LIS1 Antibody (5A5) Summary
| Immunogen |
PAFAH1B1 (NP_000421, 1 a.a. – 110 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSP
|
| Specificity |
PAFAH1B1 – platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (5A5)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PAFAH1B1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for LIS1 Antibody (5A5)
- LIS-1
- LIS1PAF-AH alpha
- LIS2
- lissencephaly 1 protein
- Lissencephaly-1 protein
- MDCR
- MDS
- Miller-Dieker syndrome chromosome region
- PAF acetylhydrolase 45 kDa subunit
- PAF-AH 45 kDa subunit
- PAFAH alpha
- PAFAH
- PAFAHA
- platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
- platelet-activating factor acetylhydrolase IB subunit alpha
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
- platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
Background
PAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq]