Kynurenine 3-Monooxygenase/KMO Antibody Summary
| Immunogen |
A synthetic peptide corresponding to an internal region between amino acids 200-299
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| Specificity |
This antibody is specific to KMO
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
KMO
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Publications |
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Reactivity Notes
This antibody is reactive in Mouse
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 50% (v/v) Glycerol
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
Immunogen affinity purified
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| Reconstitution Instructions |
Reconstitute with 185 ml of water to desired concentration and for immediate usage.
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Alternate Names for Kynurenine 3-Monooxygenase/KMO Antibody
- KMO
- kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
- Kynurenine 3Monooxygenase
- Kynurenine 3-Monooxygenase
Background
Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid is a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.