Kir3.1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human GIRK1. The exact sequence is proprietary.
|
| Localization |
Membrane, Multi-pass membrane protein
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
KCNJ3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.7 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Kir3.1 Antibody
- G protein-activated inward rectifier potassium channel 1
- GIRK-1
- GIRK1Kir3.1
- Inward rectifier K(+) channel Kir3.1
- inward rectifier K+ channel KIR3.1
- KGA
- KIR3.1
- Potassium channel, inwardly rectifying subfamily J member 3
- potassium inwardly-rectifying channel, subfamily J, member 3
Background
FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.; Subcellular location: Membrane, Multi-pass membrane protein.