Kallikrein 8/Neuropsin Antibody (2F11) Summary
| Immunogen |
KLK8 (NP_009127, 97 a.a. ~ 205 a.a) partial recombinant protein with GST tag.EIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG
|
| Specificity |
KLK8 – kallikrein 8 (neuropsin/ovasin)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
KLK8
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence and ELISA.
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Kallikrein 8/Neuropsin Antibody (2F11)
- EC 3.4.21
- EC 3.4.21.118
- hK8
- HNP
- kallikrein 8 (neuropsin/ovasin)
- Kallikrein 8
- kallikrein-related peptidase 8
- KLK8 protein type 1
- KLK8 protein type 2
- KLK8
- neuropsin type 1
- neuropsin type 2
- Neuropsin
- NP
- NRPN
- Ovasin
- PRSS19
- PRSS19kallikrein-8
- Serine protease 19
- Serine protease TADG-14
- TADG14neuropsin
- Tumor-associated differentially expressed gene 14 protein
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.