KOR Antibody Summary
| Immunogen |
Peptide with sequence C-PAYLRDIDGMNKP corresponding to C-Terminus according to NP_000903.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
OPRK1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 45 kDa band observed in human brain (cerebral cortex) lysates (calculated MW of 42.6 kDa band according to NP_000903.2). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 27523794).
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| Theoretical MW |
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for KOR Antibody
- kappa opioid receptor
- kappa-type opioid receptor
- KOR
- K-OR-1
- KOR-1
- Opiate receptor, kappa-1
- opioid receptor, kappa 1
- OPRK
- OPRK1
- Oprk2
- R21
Background
Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacologic studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors.