JNK1 Antibody (4A11) Summary
| Immunogen |
MAPK8 (NP_620637 318 a.a. – 427 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR
|
| Specificity |
MAPK8 – mitogen-activated protein kinase 8 (4A11)
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MAPK8
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for JNK1 Antibody (4A11)
- c-Jun N-terminal kinase 1
- EC 2.7.11
- EC 2.7.11.24
- JNK1 alpha protein kinase
- JNK1 beta protein kinase
- JNK1
- JNK1JNK1A2
- JNK-46
- JUN N-terminal kinase
- MAP kinase 8
- MAPK 8
- MAPK8
- mitogen-activated protein kinase 8 isoform JNK1 alpha1
- mitogen-activated protein kinase 8 isoform JNK1 beta2
- mitogen-activated protein kinase 8
- PRKM8
- PRKM8JNK
- protein kinase JNK1
- SAPK1
- SAPK1JNK21B1/2
- Stress-activated protein kinase 1
- Stress-activated protein kinase JNK1
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]