Integrin beta 7 Antibody (332408) Summary
| Immunogen |
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin beta 7
Glu20-His722 Accession # P26011 |
| Specificity |
Detects mouse Integrin beta 7 extracellular domain in direct ELISAs.
|
| Source |
N/A
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| Isotype |
IgG2a
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| Clonality |
Monoclonal
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| Host |
Rat
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| Gene |
ITGB7
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| Purity |
Protein A or G purified from hybridoma culture supernatant
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| Endotoxin Note |
<0.10 EU per 1 μg of the antibody by the LAL method.
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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| Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
|
| Preservative |
No Preservative
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| Concentration |
LYOPH
|
| Purity |
Protein A or G purified from hybridoma culture supernatant
|
| Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS.
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Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Integrin beta 7 Antibody (332408)
- Gut homing receptor beta subunit
- integrin beta 7 subunit
- Integrin beta 7
- integrin beta-7
- integrin, beta 7
- ITGB7
Background
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.