Product: 5-Nonylphenol polyethoxylate
Integrin alpha 4/CD49d Antibody (9C10 (MFR.4.B)) [DyLight 680] Summary
Immunogen |
Mouse LyD9 haematopoietic progenitor cells
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Localization |
Type I membrane protein
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Specificity |
NB100-64905 recognizes murine alpha 4 integrin (CD49d), a 150kD glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1. Clone 9C10 (MFR4.B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2 (1) Removal of sodium azide is recommended prior to use in functional assays.
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Isotype |
IgG2a
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Clonality |
Monoclonal
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Host |
Rat
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Gene |
ITGA4
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Purity |
Protein G purified
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Applications/Dilutions
Dilutions |
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Application Notes |
Optimal dilution of this antibody should be experimentally determined.
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark.
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Buffer |
50mM Sodium Borate
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Preservative |
0.05% Sodium Azide
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Purity |
Protein G purified
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Notes
Alternate Names for Integrin alpha 4/CD49d Antibody (9C10 (MFR.4.B)) [DyLight 680]
- 269C wild type
- CD49 antigen-like family member D
- CD49d antigen
- CD49d
- CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor
- IA4
- Integrin alpha 4
- integrin alpha-4 subunit
- integrin alpha-4
- Integrin alpha-IV
- integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- ITGA4
- MGC90518
- very late activation protein 4 receptor, alpha 4 subunit
- VLA-4 subunit alpha
- VLA-4