Influenza B Virus Nucleoprotein Antibody (1B6) – BSA Free Summary
| Immunogen |
Unpurified influenza B virus (B/Lee/40) for primary intranasal immunization, boosted intravenously with purified influenza B virus disrupted with Triton X-100 for 40 min at 37 degrees C.
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| Specificity |
Reacts with influenza B virus nucleoprotein as demonstrated by immunoblotting after SDS-PAGE. Does not cross-react with influenza A virus (2)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Purity |
Protein A or G purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Virus
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
10mM Phosphate (pH 7.4) and 0.5M NaCl
|
| Preservative |
15mM Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Protein A or G purified
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Alternate Names for Influenza B Virus Nucleoprotein Antibody (1B6) – BSA Free
- Influenza B Virus NP
- NP
- Nucleoprotein
Background
Influenza viruses are common and highly infectious human pathogens. They are constantly mutating to modify their antigenicity and avoid elimination by immunity to previous generations of virus. The nucleoprotein of influenza B virus is a basic, phosphorylated multimeric protein consisting of 560 aa subunits that encapsidate the viral RNA genome to form a ribonucleoprotein particle (1)