IRS2 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 1288 and 1338 of human insulin receptor substrate 2 using the numbering given in entry NP_003740.2 (GeneID 8660).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
IRS2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is not recommended for Western Blot analysis.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for IRS2 Antibody
- insulin receptor substrate 2
- IRS2
- IRS-2
Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.