INTS11 Antibody

Product: 4,6-Dicaffeoylquinic acid

INTS11 Antibody Summary

Immunogen
This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
Localization
Cellular Location Nucleus. Cytoplasm.
Clonality
Polyclonal
Host
Rabbit
Gene
CPSF3L
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10 – 1:50
  • Immunohistochemistry-Paraffin 1:10 – 1:50

Reactivity Notes

Reacts with Human. Predicted to react with Bovine, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for INTS11 Antibody

  • cleavage and polyadenylation specific factor 3-like
  • Cleavage and polyadenylation-specific factor 3-like protein
  • CPSF3-like protein
  • EC 3.1.27
  • EC 3.1.27.-
  • FLJ20542
  • INT11
  • integrator complex subunit 11
  • INTS11FLJ13294
  • Protein related to CPSF subunits of 68 kDa
  • RC68
  • RC-68CPSF73L
  • related to CPSF subunits 68 kDa

Background

The Integrator complex contains at least 12 subunits andassociates with the C-terminal domain of RNA polymerase II largesubunit (POLR2A; MIM 180660) and mediates the 3-prime endprocessing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2(RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit ofthe Integrator complex (Baillat et al., 2005 [PubMed16239144]).

PMID: 23373701