IGF2BP3 Antibody (8F11)

Product: IPI550

IGF2BP3 Antibody (8F11) Summary

Immunogen
Purified recombinant fragment of human IGF2BP3 expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF2BP3
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200-1:1000
Theoretical MW
69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for IGF2BP3 Antibody (8F11)

  • CT98
  • hKOC
  • IGF II mRNA binding protein 3
  • IGF2 mRNA-binding protein 3
  • IGF-II mRNA-binding protein 3
  • IMP-3KH domain-containing protein overexpressed in cancer
  • IMP3VICKZ family member 3
  • insulin-like growth factor 2 mRNA binding protein 3
  • insulin-like growth factor 2 mRNA-binding protein 3
  • KH domain containing protein overexpressed in cancer
  • KOC1DKFZp686F1078
  • VICKZ3cancer/testis antigen 98

Background

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5 UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq]

PMID: 16604191