ICAM-3/CD50 Antibody (ICAM3/1019) – Azide and BSA Free Summary
| Immunogen |
Recombinant human ICAM3 protein
|
| Localization |
Cell surface
|
| Specificity |
Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
ICAM3
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Hu-chromosome location: 19p13.2 Molecular weight of antigen: 110-160kDa Immunohistochemistry-Paraffin 0.5 – 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
No Preservative
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for ICAM-3/CD50 Antibody (ICAM3/1019) – Azide and BSA Free
- CD50 antigen
- CD50
- CDW50CDw50
- ICAM3
- ICAM-3
- ICAM-Rintercellular adhesion molecule-3
- intercellular adhesion molecule 3