Hsp47 Antibody Summary
| Immunogen |
SERPINH1 (NP_001226.2, 1 a.a. – 418 a.a.) full-length human protein. MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
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| Specificity |
SERPINH1 – serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1),
|
| Clonality |
Polyclonal
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| Host |
Mouse
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| Gene |
SERPINH1
|
| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control. It is also useful for IF.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Hsp47 Antibody
- (collagen binding protein 1)
- Arsenic-transactivated protein 3
- AsTP3
- BERF-1
- CBP1
- CBP2
- CBP2RA-A47
- Cell proliferation-inducing gene 14 protein
- Collagen-binding protein
- colligen
- Colligin
- colligin-1
- colligin-2
- gp46
- HSP47
- HSP47serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47)
- member 1, (collagen binding protein 1)
- member 2
- member 2, (collagen-binding protein 2)
- OI10
- PPROM
- proliferation-inducing gene 14
- RA-A47
- rheumatoid arthritis antigen A-47,47 kDa heat shock protein
- Rheumatoid arthritis-related antigen RA-A47
- serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47)
- Serpin H1
- serpin peptidase inhibitor, clade H (heat shock protein 47), member 1
- SERPINH1
- SERPINH2colligin
Background
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. [provided by RefSeq]