Haemophilus Influenzae B Antibody (1079/457)

Product: Pheniramine (Maleate)

Haemophilus Influenzae B Antibody (1079/457) Summary

Immunogen
Native, NCTC 7279
Specificity
NB100-64551 recognizes Haemophilus influenzae B, a gram-negative coccobacillus that is the cause of bacterial meningitis and other severe illnesses in young children.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Haemophilus Influenzae B Antibody (1079/457)

  • H. influenza B

Background

Haemophilus influenzae is a small, nonmotile Gram negative bacterium found naturally in the nasopharynx of approximately 75 percent of healthy children and adults. The presence of the type B polysaccharide capsule is the major factor in virulence. Encapsulated organisms can penetrate the epithelium of the nasopharynx and invade the blood capillaries directly. Their capsule allows them to resist phagocytosis and complement mediated lysis in the the nonimmune host and cause bacteremia and acute bacterial meningitis in infants and young children. Occasionally epiglottitis cellulitis, osteomyelitis, and joint infections can be caused.

PMID: 18374160