Product: Pantoprazole (sodium)
HSPB8/HSP22 Antibody (5B12) Summary
| Immunogen |
HSPB8 (NP_055180, 97 a.a. ~ 197 a.a) partial recombinant protein with GST tag. KVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
|
| Specificity |
HSPB8 (5B12)
|
| Isotype |
IgG Mix Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
HSPB8
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for ELISA and immunohistochemistry (paraffin).
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
In 1x PBS, pH 7.4
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for HSPB8/HSP22 Antibody (5B12)
- Alpha-crystallin C chain
- CMT2L
- CRYAC
- DHMN2
- E2IG1
- E2IG1E2-induced gene 1 protein
- H11
- H11DHMN2
- heat shock 22kDa protein 8
- heat shock 27kDa protein 8
- heat shock protein beta-8
- HMN2
- HMN2A
- HSP22
- HSP22CMT2L
- HSPB8
- Protein kinase H11
- Small stress protein-like protein HSP22
Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.