HSP90 beta Antibody (4C10)

Product: Pargyline (hydrochloride)

HSP90 beta Antibody (4C10) Summary

Immunogen
Protein expressed in 293T cell transfected with human HSP90AB1 expression vector
Specificity
This antibody is specific for Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1).
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
HSP90AB1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000

Reactivity Notes

Human, Canine, Rat, Primate

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HSP90 beta Antibody (4C10)

  • D6S182
  • Heat shock 84 kDa
  • heat shock 90kD protein 1, beta
  • heat shock 90kDa protein 1, beta
  • heat shock protein 90kDa alpha (cytosolic), class B member 1
  • heat shock protein beta
  • heat shock protein HSP 90-beta
  • HSP 84
  • HSP84
  • HSP90 beta
  • HSP90AB1
  • HSP90B
  • HSP90-BETA
  • HSP90BHSP 90
  • HSPC2
  • HSPC2D6S182
  • HSPCB
  • HSPCBFLJ26984

Background

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219)

PMID: 23116495