HNF-4 gamma/NR2A2 Antibody

Product: Febuxostat D11

HNF-4 gamma/NR2A2 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from ligand-binding domain of human HNF4G.
Specificity
Human HNF4G. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Opossum (94%), Hamster (94%), Canine (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
HNF4G
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (94%), Panda (94%), Platypus (94%), Equine (88%), Turkey (88%), Chicken (88%), Lizard (82%), Seabass (82%), Pufferfish (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HNF-4 gamma/NR2A2 Antibody

  • hepatocyte nuclear factor 4, gamma
  • hepatocyte nuclear factor 4-gamma
  • HNF4 gamma
  • HNF-4 gamma
  • HNF4G
  • HNF-4-gamma
  • NR2A2
  • NR2A2Nuclear receptor subfamily 2 group A member 2
  • NR2A3

Background

Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 – 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver.

PMID: 23115182