HE4/WFDC2 Antibody Summary
| Immunogen |
Peptide with sequence GAEKTGVCPELQADQ corresponding to internal region according to NP_006094.3.
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| Epitope |
GAEKTGVCPELQADQ – internal region
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
WFDC2
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: In transfected HEK293 transiently expressing full-length human WFDC2 (myc and DYKDDDDK tagged), a band of approx. 25 kDa band was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody.
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Canine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Notes
Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at [email protected] for more details.
Alternate Names for HE4/WFDC2 Antibody
- dJ461P17.6
- EDDM4
- Epididymal secretory protein E4
- epididymis-specific, whey-acidic protein type, four-disulfide core
- HE4
- HE4MGC57529
- Major epididymis-specific protein E4
- Putative protease inhibitor WAP5
- WAP domain containing protein HE4-V4
- WAP four-disulfide core domain 2
- WAP four-disulfide core domain protein 2
- WAP5
- WAP5epididymal protein 4
- WFDC2
Background
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.