HAGHL Antibody (8.IGSH) Summary
| Immunogen |
Thiol-modified glutathione conjugated to KLH.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
HAGHL
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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| Publications |
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Reactivity Notes
Recognizes mammals Glutathione NEM. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2) and 0.1mM PMSF
|
| Preservative |
No Preservative
|
| Purity |
Protein A or G purified
|
Alternate Names for HAGHL Antibody (8.IGSH)
- EC 3.1.2.-
- GLO2-like/ RJD12
- hydroxyacyl glutathione hydrolase-like
- hydroxyacylglutathione hydrolase-like protein
- hydroxyacylglutathione hydrolase-like
- MGC2605
Background
Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinsons disease.