Glutathione Peroxidase 3/GPX3 Antibody Summary
| Immunogen |
Peptide with sequence C-NQFGKQEPGENSE corresponding to internal region according to NP_002075.2.
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| Epitope |
NQFGKQEPGENSE
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| Specificity |
This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
GPX3
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 26 kDa band observed in mouse kidney and liver lysates (calculated MW of 27.7 kDa band according to mouse NP_001077398.1 [isoform1], 25.4 kDa band according to mouse NP_032187.2 [isoform 2] and 25.5 kDa band according to human NP_002075.2). IHC-Fr: Porcin kidney shows vesicular staining of the cytoplasm in PCT epithelial cells.
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Human, Rat, Canine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Glutathione Peroxidase 3/GPX3 Antibody
- EC 1.11.1
- EC 1.11.1.9
- Extracellular glutathione peroxidase
- glutathione peroxidase 3 (plasma)
- Glutathione Peroxidase 3
- GPX3
- GPx-3
- GPXP
- GPX-P
- GSHPx-3
- GSHPx-P
- Plasma glutathione peroxidase
Background
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.