Glutathione Peroxidase 3/GPX3 Antibody

Product: (-)-DHMEQ

Glutathione Peroxidase 3/GPX3 Antibody Summary

Immunogen
Peptide with sequence C-NQFGKQEPGENSE corresponding to internal region according to NP_002075.2.
Epitope
NQFGKQEPGENSE
Specificity
This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6
Clonality
Polyclonal
Host
Goat
Gene
GPX3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 – 3 ug/ml
  • Immunohistochemistry 20 ug/ml
  • Peptide ELISA Detection limit 1:1000
Application Notes
WB: Approx. 26 kDa band observed in mouse kidney and liver lysates (calculated MW of 27.7 kDa band according to mouse NP_001077398.1 [isoform1], 25.4 kDa band according to mouse NP_032187.2 [isoform 2] and 25.5 kDa band according to human NP_002075.2). IHC-Fr: Porcin kidney shows vesicular staining of the cytoplasm in PCT epithelial cells.
Positive Control
Heart Lysate (NB820-59660)
Publications
Read Publication using NB100-57858.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Glutathione Peroxidase 3/GPX3 Antibody

  • EC 1.11.1
  • EC 1.11.1.9
  • Extracellular glutathione peroxidase
  • glutathione peroxidase 3 (plasma)
  • Glutathione Peroxidase 3
  • GPX3
  • GPx-3
  • GPXP
  • GPX-P
  • GSHPx-3
  • GSHPx-P
  • Plasma glutathione peroxidase

Background

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

PMID: 24666365