Product: Caspofungin (Acetate)
GluR1 Antibody (RH95) Summary
| Immunogen |
Peptide corresponding to amino acid residues from the N-terminal region of rat GluR1.
|
| Specificity |
Specific for the ~105k GluR1 protein.
|
| Preparation Method |
Protein G purified culture supernatant
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
GRIA1
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
The antibody has been directly tested for reactivity in Western blots with mouse and rat tissue. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
|
| Preservative |
No Preservative
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein G purified
|
Alternate Names for GluR1 Antibody (RH95)
- AMPA 1
- AMPA-selective glutamate receptor 1
- GluA1
- GLUH1
- GluR1
- gluR-1
- GLUR1gluR-A
- GLURA
- GluR-A
- gluR-K1
- glutamate receptor 1
- Glutamate receptor ionotropic, AMPA 1
- glutamate receptor, ionotropic, AMPA 1
- GRIA1
- HBGR1
- MGC133252
Background
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinanen et al., 1990;Hollmann and Heinemann, 1994).