GluR1 Antibody (RH95)

Product: Caspofungin (Acetate)

GluR1 Antibody (RH95) Summary

Immunogen
Peptide corresponding to amino acid residues from the N-terminal region of rat GluR1.
Specificity
Specific for the ~105k GluR1 protein.
Preparation
Method
Protein G purified culture supernatant
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GRIA1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Theoretical MW
105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

The antibody has been directly tested for reactivity in Western blots with mouse and rat tissue. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for GluR1 Antibody (RH95)

  • AMPA 1
  • AMPA-selective glutamate receptor 1
  • GluA1
  • GLUH1
  • GluR1
  • gluR-1
  • GLUR1gluR-A
  • GLURA
  • GluR-A
  • gluR-K1
  • glutamate receptor 1
  • Glutamate receptor ionotropic, AMPA 1
  • glutamate receptor, ionotropic, AMPA 1
  • GRIA1
  • HBGR1
  • MGC133252

Background

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinanen et al., 1990;Hollmann and Heinemann, 1994).

PMID: 12217360