GUCY2D Antibody (1E6.)

Product: DFMTI

GUCY2D Antibody (1E6.) Summary

Immunogen
GUCY2D (NP_000171, 521 a.a. – 630 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL
Specificity
GUCY2D – guanylate cyclase 2D, membrane (retina-specific)
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
GUCY2D
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GUCY2D Antibody (1E6.)

  • CORD6cone rod dystrophy 5/6
  • CYGD
  • EC 4.6.1
  • guanylate cyclase 2D, membrane (retina-specific)
  • Guanylate cyclase 2D, retinal
  • GUC1A4
  • GUC2DCORD5
  • LCA
  • LCA1RCD2
  • retGC
  • RETGC1
  • RETGC-1EC 4.6.1.2
  • retinal guanylyl cyclase 1
  • Rod outer segment membrane guanylate cyclase
  • ROSGC
  • ROS-GC
  • ROS-GC1

Background

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]

PMID: 12056557