GUCY2D Antibody (1E6.) Summary
| Immunogen |
GUCY2D (NP_000171, 521 a.a. – 630 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL
|
| Specificity |
GUCY2D – guanylate cyclase 2D, membrane (retina-specific)
|
| Isotype |
IgG
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
GUCY2D
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GUCY2D Antibody (1E6.)
- CORD6cone rod dystrophy 5/6
- CYGD
- EC 4.6.1
- guanylate cyclase 2D, membrane (retina-specific)
- Guanylate cyclase 2D, retinal
- GUC1A4
- GUC2DCORD5
- LCA
- LCA1RCD2
- retGC
- RETGC1
- RETGC-1EC 4.6.1.2
- retinal guanylyl cyclase 1
- Rod outer segment membrane guanylate cyclase
- ROSGC
- ROS-GC
- ROS-GC1
Background
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]