GTF2A1L Antibody (3E4) Summary
| Immunogen |
ALF (NP_006863, 251 a.a. ~ 348a.a) partial recombinant protein with GST tag.PQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVT DIQLHILKNRMYGCDSVKQPRNIEEPSNIPVSEKDSNSQVDL SIRVTDDDIGEIIQ
|
| Localization |
Nuclear
|
| Specificity |
ALF – TFIIA-alpha/beta-like factor
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
GTF2A1L
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GTF2A1L Antibody (3E4)
- 1-like factor
- general transcription factor IIA, 1-like
- GTF2A1LF
- MGC26254
- TFIIA large subunit isoform ALF
- TFIIA-alpha and beta-like factor
- TFIIA-alpha/beta-like factor
Background
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.