GPR68 Antibody Summary
| Immunogen |
Synthetic 16 amino acid peptide from C-terminus of human GPR68.
|
| Localization |
Cell membrane; Multipass membrane protein.
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| Specificity |
Human GPR68. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
|
| Clonality |
Polyclonal
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| Host |
Rabbit
|
| Gene |
GPR68
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Canine (88%), Bat (88%), Panda (88$), Platypus (88%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for GPR68 Antibody
- G protein-coupled receptor 68
- GPR12A
- G-protein coupled receptor 68
- MGC111379
- OGR-1
- OGR1MGC156983
- ovarian cancer G protein-coupled receptor, 1
- ovarian cancer G-protein coupled receptor 1
- Sphingosylphosphorylcholine receptor
Background
OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851.