GPR137B Antibody

Product: SB-505124

GPR137B Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from C-terminus of human GPR137B / TM7SF1.
Epitope
C-terminal domain of human
Specificity
Human GPR137B / TM7SF1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR137C (44%).
Predicted Species
Opossum (94%), Goat (94%), Chicken (94%), Primate (94%), Turkey (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
GPR137B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 5 – 13 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (100%), Elephant (100%), Panda (100%), Gibbon (94%), Bat (89%), Platypus (89%), Xenopus (89%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPR137B Antibody

  • G protein-coupled receptor 137B
  • TM7SF1
  • transmembrane 7 superfamily member 1 (upregulated in kidney)

Background

TM7SF1 is an Orphan-U GPCR with an unknown ligand. This receptor has been shown to be upregulated during kidney development. TM7SF1 has been reported to be expressed in adult kidney and heart, but not in fetal kidney. ESTs have been isolated from a wide variety of tissues, including B-cell/lung/testis, brain, connective tissue, ear, embryo, eye, gall bladder, kidney, liver/spleen, lung, melanocyte/uterus/fetal heart, nerve, pineal, placenta, skin, spleen, testis, tonsil, and vessel libraries.

PMID: 24919179