GNAI3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human G protein alpha Inhibitor 3. The exact sequence is proprietary.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
GNAI3
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Mouse reactivity determined by WB.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.94 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for GNAI3 Antibody
- FLJ26559
- G(i) alpha-3
- guanine nucleotide binding protein (G protein), alpha inhibiting activitypolypeptide 3,87U6
- guanine nucleotide-binding protein G(k) subunit alpha
Background
GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.