GLI-3 Antibody (2C9) Summary
| Immunogen |
GLI3 (NP_000159, 1 a.a. – 110 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFA
|
| Specificity |
GLI3 (2C9)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
GLI3
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GLI-3 Antibody (2C9)
- ACLS
- ACLSPAPAPHS
- ADD
- Bph
- GCPS
- GLI family zinc finger 3
- GLI3 form of 190 kDa
- GLI3 full length protein
- GLI3
- GLI-3
- GLI3-190
- GLI3FL
- GLI-Kruppel family member GLI3
- glioma-associated oncogene family zinc finger 3
- Greig cephalopolysyndactyly syndrome
- oncogene GLI3
- PAP-A
- PAPA1
- PAPB
- PAPBDNA-binding protein
- Pdn
- PHS
- PPDIV
- Xt
- zinc finger protein GLI3
Background
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.