GABA-A R gamma 2 Antibody

Product: BEC (hydrochloride)

GABA-A R gamma 2 Antibody Summary

Immunogen
Peptide with sequence C-NNATHLQERDE corresponding to internal region according to NP_000807.2, NP_944493.2.
Epitope
NNATHLQERDE – internal region
Specificity
This antibody is expected to recognize all reported isoforms: NP_944494.1; NP_000807.2; NP_944493.2. Note the aa numbers used in the name are from NP_944494.1.
Clonality
Polyclonal
Host
Goat
Gene
GABRG2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 – 3 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 50 kDa band observed in mouse and rat brain lysates (calculated MW of 55.1 kDa band according to mouse NP_032099.1 and 54.1 kDa band according to rat NP_899156.1).
Publications
Read Publication using NBP1-49868.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GABA-A R gamma 2 Antibody

  • CAE2
  • ECA2
  • GABA A R gamma 2
  • GABA(A) receptor subunit gamma-2
  • GABAAR gamma 2
  • GABAARg2
  • GABRG2
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • gamma-aminobutyric acid receptor subunit gamma-2
  • GEFSP3

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.

PMID: 11752097