GABA-A R alpha 1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary.
|
| Localization |
Cell junction; synapse; postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
|
| Predicted Species |
Mouse (99%), Bovine (100%), Chicken (97%), Rhesus Macaque (100%), Rabbit (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
GABRA1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Zebrafish (89%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.75 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for GABA-A R alpha 1 Antibody
- ECA4
- EJM
- EJM5GABA(A) receptor subunit alpha-1
- GABA A R alpha 1
- GABAAR alpha 1
- GABAARa1
- GABRA1
- gamma-aminobutyric acid (GABA) A receptor, alpha 1
- gamma-aminobutyric acid receptor subunit alpha-1
Background
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]