Product: 7-Maleimidohexanoic acid N-hydroxysuccinimide ester
Fibronectin Antibody (568) [HRP] Summary
| Immunogen |
High molecular weight proteins secreted by cultivated human fibroblasts
|
| Localization |
Connective tissue matrix
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| Specificity |
Epitope of this MAb is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
|
| Gene |
FN1
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
PBS
|
| Preservative |
No Preservative
|
| Purity |
Protein A or G purified
|
Alternate Names for Fibronectin Antibody (568) [HRP]
- Fibronectin
- FN1