Fibronectin/Anastellin Antibody (SPM539) [DyLight 550] Summary
| Immunogen |
Human fibronectin purified from serum by affinity chromatography on gelatin-sepharose
|
| Localization |
Connective tissue matrix
|
| Specificity |
Fibronectin is a dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
FN1
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Immunohistochemistry (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A purified
|
Alternate Names for Fibronectin/Anastellin Antibody (SPM539) [DyLight 550]
- CIGDKFZp686O13149
- Cold-insoluble globulin
- DKFZp686F10164
- DKFZp686H0342
- DKFZp686I1370
- fibronectin 1
- fibronectin
- Fibronectin/Anastellin
- FNFINC
- FNZ
- GFND2ED-B
- LETSGFND
- migration-stimulating factor
- MSF