Fc gamma RIIB/CD32b Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD32B. The exact sequence is proprietary.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
FCGR2B
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Fc gamma RIIB/CD32b Antibody
- CD32 antigen
- CD32b
- CD32Fc fragment of IgG, low affinity II, receptor for (CD32)
- CDw32
- Fc fragment of IgG, low affinity IIb, receptor (CD32)
- Fc fragment of IgG, low affinity IIb, receptor for (CD32)
- Fc gamma RIIB
- FCG2
- Fc-gamma RII-b
- fc-gamma-RIIb
- FCGR2
- FCGR2B
- FcgRIIB
- FCRIIB
- fcRII-b
- IGFR2
- IgG Fc receptor II-b
- low affinity immunoglobulin gamma Fc region receptor II-b
Background
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]