Fc gamma RI/CD64 Antibody (10.1) [FITC] Summary
| Immunogen |
Rheumatoid synovial fluid cells and fibronectin purified human monocytes.
|
| Localization |
Type I membrane protein.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
FCGR1A
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Flow Cytometry Use 10ul of this working dilution for 10sup6/sup cells. Optimal dilutions/concentrations should be determined by the end user.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein G purified
|
Alternate Names for Fc gamma RI/CD64 Antibody (10.1) [FITC]
- CD64 antigen
- CD64
- Fc fragment of IgG, high affinity Ia, receptor (CD64)
- Fc gamma RI
- FCG1
- Fc-gamma receptor I B2
- Fc-gamma RI
- Fc-gamma RIA
- FcgammaRIa
- FCGR1
- FcgRI
- FCRI
- FLJ18345
- high affinity Ia, receptor for (CD64)
- high affinity immunoglobulin gamma Fc receptor I
- IgG Fc receptor I
Background
The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. Monocytes and macrophages express CD64, while mature granulocytes and lymphocytes are negative.