Fc gamma RI/CD64 Antibody (10.1) Summary
| Immunogen |
Rheumatoid synovial fluid cells and fibronectin purified human monocytes.
|
| Localization |
Type I membrane protein.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
FCGR1A
|
| Purity |
Protein G purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||
| Theoretical MW |
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
||
| Positive Control |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein G purified
|
Notes
Positive control(s): Myeloid cell lines U937 and HL60.
Alternate Names for Fc gamma RI/CD64 Antibody (10.1)
- CD64 antigen
- CD64
- Fc fragment of IgG, high affinity Ia, receptor (CD64)
- Fc gamma RI
- FCG1
- Fc-gamma receptor I B2
- Fc-gamma RI
- Fc-gamma RIA
- FcgammaRIa
- FCGR1
- FcgRI
- FCRI
- FLJ18345
- high affinity Ia, receptor for (CD64)
- high affinity immunoglobulin gamma Fc receptor I
- IgG Fc receptor I
Background
The high affinity receptor for immunoglobulin G CD64 is encoded by a family of 3 genes that share over 98% of DNA sequence homology: FCGR1A, FCGR1B and FCGR1C. The FCGR1C gene, like FCGR1A, is located on 1q21. The third gene of this family, FCGR1B, was found at 1p12. CD64 plays a pivotal role in the immune response. It is a glycoprotein (MW 72 kD) that is constitutively expressed on human monocytes and macrophages.