Product: Ceftriaxone (sodium salt)
Fc epsilon RI Antibody (9E1) [DyLight 755] Summary
| Immunogen |
Made to Human Fc EPSILON R1 ALPHA
|
| Localization |
Membrane; single pass type I membrane protein.
|
| Specificity |
NB100-63269 recognizes the human high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Clone 9E1 specifically recognizes the extracellular D1 domain of the Fc epsilon R1 alpha chain. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
FCER1A
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Fc epsilon RI Antibody (9E1) [DyLight 755]
- alpha polypeptide
- Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
- Fc-epsilon RI-alpha
- FcERI
- high affinity immunoglobulin epsilon receptor alpha-subunit
- high affinity immunoglobulin epsilon receptor subunit alpha
- high-affinity, of mast cells, alpha polypeptide