FHL1 Antibody Summary
| Immunogen |
Peptide with sequence CTVSRVSHPVSKARK corresponding to internal region according to AAC72886.1.
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| Specificity |
This antibody is specific for the FHL-1 isoform B (SLIMMER) and is expected to recognise an epitope corresponding to aa 233-246 of human SLIMMER protein.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
FHL1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 30 kDa band observed in human heart lysates (calculated MW of 36.3 kDa band according to AAC72886) is consistent with scientific literature (PMID: 1048092).
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Canine. Mouse reactivity reported in scientific literature (PMID: 24614889).
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for FHL1 Antibody
- bA535K18.1
- FHL1
- four and a half LIM domains 1
- HLH1
- HPLH1
- KYOT
- KYO-T
- LIM protein SLIMMER
- skeletal muscle LIM-protein1
- SLIM1
- SLIM1Isl-1 and Mec-3 domains 1
- SLIMMER
- XMPMA
Background
LIM proteins, named for LIN11, ISL1 and MEC3 are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. FHL1 may have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP J and plays a negative regulatory role in the RBP J mediated transcription in mammalian systems.