Product: MI 2 (MALT2 inhibitor)
FGF-8 Antibody Summary
| Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminal of human FGF8, identical to the related rat and mouse sequence.
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| Specificity |
The antigen sequence is identical among mouse and rat.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
FGF8
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
0.2 mg DiSodium Phosphate, 0.9 mg NaCl and 5 mg BSA
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| Preservative |
0.05mg Thimerosal, 0.05mg Sodium Azide
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| Concentration |
LYOPH
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| Purity |
Immunogen affinity purified
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| Reconstitution Instructions |
Reconstitute with 0.1 ml distilled water.
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Alternate Names for FGF-8 Antibody
- AIGF
- AIGFKAL6
- Androgen-induced growth factor
- FGF8
- FGF-8
- fibroblast growth factor 8 (androgen-induced)
- fibroblast growth factor 8
- HBGF-8
- Heparin-binding growth factor 8
- MGC149376
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.