EphB6 Antibody (2A6B9)

Product: Scutellarin

EphB6 Antibody (2A6B9) Summary

Immunogen
Purified recombinant fragment of EPH Receptor B6 (2A6B9) expressed in E. Coli.
Specificity
Specific for EPH Receptor B6.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
EPHB6
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • Western Blot 1: 500-1: 2000
  • ELISA 1: 10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1: 200-1: 1000
  • Immunohistochemistry-Paraffin 1: 200-1: 1000

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for EphB6 Antibody (2A6B9)

  • EC 2.7.10.1
  • EPH receptor B6
  • EphB6
  • ephrin type-B receptor 6
  • Hep
  • HEPTyrosine-protein kinase-defective receptor EPH-6
  • Mep
  • MGC129910
  • MGC129911

Background

EPH receptor B6. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

PMID: 25528965