Product: Dasatinib (hydrochloride)
EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)) [Alexa Fluor® 488] Summary
| Immunogen |
Recombinant human Ep-CAM protein (full-length and fragments)
|
| Localization |
Cell surface
|
| Marker |
Epithelial Marker
|
| Specificity |
It is a cocktail of four highly specific monoclonal antibodies (EGP40/826, EGP40/837, EGP40/1110, EGP40/1120) that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (Ep-CAM). It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or Ep-CAM. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TACSTD1, EPCAM
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Alternate Names for EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)) [Alexa Fluor® 488]
- 17-1A
- 323/A3
- ACSTD1
- antigen identified by monoclonal AUA1
- CD326 antigen
- CD326
- Cell surface glycoprotein Trop-1
- chromosome 4, surface marker (35kD glycoprotein)
- DIAR5
- EGP
- EGP-2
- EGP314
- EGP40
- EpCAM
- epithelial cell adhesion molecule
- Epithelial cell surface antigen
- Epithelial glycoprotein 314
- Epithelial glycoprotein
- ESA
- GA733-2
- GA733-2EGP34
- gp40
- hEGP314
- HNPCC8
- KS 1/4 antigen
- KS1/4
- KSAHEA125
- M1S2
- M4S1
- M4S1Ly74
- Major gastrointestinal tumor-associated protein GA733-2
- MIC18MH99
- MOC31
- TACST-1
- TACSTD1
- TROP1
- TROP1CD326
- Tumor-associated calcium signal transducer 1CO-17A