EZH1 Antibody Summary
| Immunogen |
Peptide with sequence EIPNPPTSKCITY corresponding to N-Terminus according to NP_001982.2.
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| Localization |
Nuclear
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
EZH1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 85 kDa band observed in lysate of cell line MOLT4 (calculated MW of 85.3 kDa band according to NP_001982.2).
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for EZH1 Antibody
- EC 2.1.1.43
- enhancer of zeste homolog 1 (Drosophila)
- Enhancer of zeste homolog 1
- ENX-2
- histone-lysine N-methyltransferase EZH1
- KIAA0388enhancer of zeste (Drosophila) homolog 1
- KMT6B
Background
EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin.