ERK3/MAPK6 Antibody (5E1) Summary
| Immunogen |
Recombinant protein expressed in E.coli corresponding to amino acids 345-721 of human ERK3
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| Specificity |
This antibody is specific for Homo sapiens mitogen-activated protein kinase 6 (MAPK6).
|
| Isotype |
IgG2a
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MAPK6
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for ERK3/MAPK6 Antibody (5E1)
- DKFZp686F03189
- EC 2.7.11
- EC 2.7.11.24
- ERK3
- ERK-3
- ERK3p97-MAPK
- Extracellular signal-regulated kinase 3
- extracellular signal-regulated kinase, p97
- HsT17250
- MAP kinase 6
- MAP kinase isoform p97
- MAPK 6
- MAPK6
- mitogen-activated protein kinase 6
- p97MAPK
- PRKM6
- protein kinase, mitogen-activated 5
- protein kinase, mitogen-activated 6
Background
ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters