EBV Early Antigens Antibody (1108-1) [HRP]

Product: NVP-LCQ196

EBV Early Antigens Antibody (1108-1) [HRP] Summary

Immunogen
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitts lymphoma sera
Localization
Nuclear
Specificity
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry-Frozen
Readout System
  • NovaLume Plus Chemiluminescent Reagent

Reactivity Notes

Epstein-Barr virus

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

PMID: 26514586