Dihydrolipoamide Dehydrogenase/DLD Antibody (3C1) Summary
| Immunogen |
DLD (AAH18696, 1 a.a. – 509 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF
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| Specificity |
DLD – dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex)
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| Isotype |
IgG3 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
DLD
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Dihydrolipoamide Dehydrogenase/DLD Antibody (3C1)
- 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex)
- branched chain keto acid dehydrogenase complex
- Diaphorase
- dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex
- Dihydrolipoamide Dehydrogenase
- dihydrolipoamide dehydrogenasemitochondrial
- DLD
- DLDD
- DLDH
- E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex
- E3
- EC 1.8.1
- EC 1.8.1.4
- GCSL
- Glycine cleavage system L protein
- glycine cleavage system protein L
- LAD
- Lipoamide Dehydrogenase
- lipoamide reductase
- lipoyl dehydrogenase
- PHE3
Background
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.