Desmoglein-2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human Desmoglein 2. The exact sequence is proprietary.
|
| Localization |
Cell membrane, Cell junction, desmosome
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
DSG2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Desmoglein-2 Antibody
- ARVC10
- ARVD10
- Cadherin family member 5
- CDHF5
- CDHF5MGC117034
- CMD1BB
- desmoglein 2
- Desmoglein2
- Desmoglein-2
- DSG2
- HDGC
- MGC117036
- MGC117037
Background
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.